JD基本信息
岗位职责
Develop and optimize scalable protein expression systems (bacterial, mammalian, insect) for recombinant protein, antibody, and membrane protein production. Strong experience in expression troubleshooting and optimization.
Perform and automate high-throughput protein purification, including affinity chromatography, IEX and SEC.
Integrate and operate robotic platforms and liquid handling systems to streamline gene to protein workflows.
Collaborate with automation, informatics, and data science teams to support closed-loop, AI-guided experimentation.
Ensure data quality, reproducibility, and proper documentation; drive continuous process optimization.
Develop robust data management strategies, including LIMS integration, to support automation workflows.
Evaluate and adopt emerging automation technologies to advance molecular biology capabilities.
Ensure compliance with lab safety and regulatory requirements for automated systems.
Occasional domestic or international travel may be required.
任职要求
Master in Molecular Biology, Synthetic Biology, Bioengineering, Biochemistry, or related fields.
5+ years of hands-on lab experience in molecular cloning, protein expression, and purification in an HTE environment.
Proficiency with automation platforms (e.g., Tecan, Hamilton, Labcyte Echo) and automation workflow development is a plus.
Proven expertise in recombinant protein/antibody production and purification techniques.
Familiarity with protein analytics (SDS-PAGE, Western blot, HPLC, Octet/Biacore, MS, IEF).
Strong lab automation protocol design, analytical and troubleshooting skills for optimizing automated protocols.
Working knowledge of LIMS and digital lab infrastructure.
Experience operating or integrating automated instruments (e.g., qPCR, NGS, flow cytometry)
Excellent communication and teamwork abilities for cross-functional collaboration.
工作城市:
上海,招聘1人,详细地址:张江路88号